What is a common side effect of long-term corticosteroid therapy?

What is a common side effect of long-term corticosteroid therapy?

• A. Weight loss
• B. Cushing's syndrome
• C. Hypoglycemia
• D. Decreased appetite

Answer: (B)

Long-term corticosteroid therapy is associated with Cushing's syndrome, which is a significant condition that arises due to excess cortisol in the body, often as a result of prolonged exposure to glucocorticoids. This therapy mimics the action of cortisol, leading to various metabolic changes that result in symptoms characteristic of Cushing's syndrome. These can include weight gain, particularly in the central region of the body, a rounded face, and skin changes, among others. The development of Cushing's syndrome occurs because corticosteroids can increase glucose production, affect fat distribution, and alter protein metabolism. Therefore, the side effects associated with long-term corticosteroid use can be extensive, with Cushing's syndrome being one of the most notable and concerning.

Long-term corticosteroid therapy is associated with Cushing's syndrome, which is a significant condition that arises due to excess cortisol in the body, often as a result of prolonged exposure to glucocorticoids. This therapy mimics the action of cortisol, leading to various metabolic changes that result in symptoms characteristic of Cushing's syndrome. These can include weight gain, particularly in the central region of the body, a rounded face, and skin changes, among others.

The development of Cushing's syndrome occurs because corticosteroids can increase glucose production, affect fat distribution, and alter protein metabolism. Therefore, the side effects associated with long-term corticosteroid use can be extensive, with Cushing's syndrome being one of the most notable and concerning.